STK35 Antibody, Biotin conjugated

Code CSB-PA851552LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) STK35 Polyclonal antibody
Uniprot No.
Target Names
STK35
Alternative Names
CLIK-1 antibody; Clik1 antibody; CLP 36 interacting kinase antibody; CLP-36-interacting kinase 1 antibody; EC 2.7.1.37 antibody; PDLIM1 interacting kinase antibody; PDLIM1-interacting kinase 1 antibody; Serine threonine kinase 35 long form antibody; Serine/threonine kinase 35 antibody; Serine/threonine protein kinase 35 antibody; Serine/threonine-protein kinase 35 antibody; Serine/threonine-protein kinase 35 L1 antibody; STK35 antibody; STK35_HUMAN antibody; STK35L1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Serine/threonine-protein kinase 35 protein (1-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. STK35 knockdown enhanced apoptosis. Expression of the active forms and the activity of two major executioner caspases, caspase 3 and caspase 7, were also increased in osteosarcoma cells with STK35 silenced. PMID: 29414823
  2. constitutive overexpression of STK35 proteins enhances caspase-independent cell death under oxidative stress conditions. PMID: 21964068
  3. by regulating CDKN2A and inhibiting G1- to S-phase transition STK35L1 may act as a central kinase linking the cell cycle and migration of endothelial cells PMID: 21283756
  4. analysis of the STK35L proteins in human and in sea squirts PMID: 19756140
  5. results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers PMID: 11973348

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Subcellular Location
Nucleus. Nucleus, nucleolus. Cytoplasm.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Expressed in testis.
Database Links

HGNC: 16254

OMIM: 609370

KEGG: hsa:140901

STRING: 9606.ENSP00000370891

UniGene: Hs.100057

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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